To be honest with you, I'd either frankenslot Tactics with Gaussian's Synchronized Fire-Control end/ToHit, Adjusted targetting end/tohit and Adjusted Targetting ToHit Buff for the dmg bonus (or Gaussian's ToHit Buff for extra speed, up to you) although my goal would be to allocate 3 Cytoskeleton Exposure Hamidon Origin Ehnancements.
I always use Kismet on my Combat Jumping because the Kismet is on as long as CJ is on, so it's the easiest choice to put it. Same would happen with any defensive toggle such as Maneuvers, Weave, Phalanx Fighting, Grant Cover or Gymnastics from Tactical Arrow. It would also work with Hover but having Hover always on during a fight is something I wouldn't do myself because it's way too slow. If you slot it on a pasive def power that is always on, such as Agile, Doge, Lucky, Tough Hide (I don't think there are others) then it would be always on no matter what, like the Numina or Miracle procs.
I know most of the above examples are melee powers, for Blasters in general I'd say Combat Jumping is the best option, then Hover and then probably Maneuvers (unless Tactical Arrow where Gymnastics would be my first choice).
Slotted Tactics up with 4/6 Gaussian (1,2,3, and 5) and 2/6 Adjusted Targeting (1 and 5), then slotted the Kismet into Stealth. The Kismet in Stealth (appears) to be 'always on' so long as Stealth is toggled on.
I've posted my setup for how to get this slotted a couple of times now, but like Nightmarer said, you can put Kismet into any toggle power that takes Defense sets, and it'll work as long as the toggle is on.