So, update #1.
I finally hit 50 yesterday, and over the past few days (since I hit lvl 47) I've been working on getting my enhancements together. I've decided to go with @Auroxis build for the most part.
I skipped resurrect and took Tactics instead as whenever I group and someone dies, they either already have a self rez, or they just release and run back, so I've not actually used it.
I'm also looking at swapping my Alpha to Spiritual instead of Vigor. It seems like the added recharge will be better over all then the plus to healing as more recharge mean faster buffs on more people and more uptime on the End/ HP buffs for the whole team.
Status so far. Spent over 100 million and got All my Empathy slots filled with the desired set enhancements (with the exception of Heal Other. I'm using Doctored Wounds until I can get another set of Panacea for it. I've gotten all the other random slots filled and only need 19 more enhancements (almost all in attacks) to complete the build.
So now the question is what's the best path for Incarnate?
As I said above, I'm thinking of going Spiritual, Clarion, Radioactive (as all my Radiation attacks already bypass some def so the damage resist debuff seems good), Lore (I have no idea), Void (to combo with Atomic Blast), and lastly support. Would appreciate any advice on my choices and the thinking behind the advise. I don't want to screw these up, but so far I'm enjoying the build.
Soloing missions is very doable, and much easier with some of the new enhancements. Hoping it gets easier once I have more of my damaging powers slotted correctly. I've been having no issues with being the only defender in War Zone Raids/ Task Forces/ farming groups.