Ideally I'd like to have as much healing as a can specifically from doing damage and all other defense outside of that is just a bonus but it doesn't seem like there's much in the way of options on that front
I'm not super attached to a particular theme yet, I'm more interested in having a build in mind and then creating a theme around what works more than anything.
From what I've seen my best bet would be either Dark Melee/Dark Armor or Dark Melee/Bio Armor. I want to make sure there isn't something I'm missing or something I haven't considered like additional powersets or how much the archetypes affect said powersets.