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Not too sure about brute.  I've got a TW/Bio scrapper that I love, but feel guilty playing because it's so OP.

 

If I were you:

  1. Drop defense sweep and replace with crushing blow.  CB completes your ST rotation and is the fastest power you have to gain momentum 
  2. Drop SJ and replace with titan sweep. You already have combat teleport and teleport. TS completes your aoe rotation and hits hard.   
  3. Drop the enhancement chase for +regen and replace with global -rech and -rech in your heal/regen/absorb powers.  Getting your click powers up as fast as possible is the key to Bio. 
  4. Consider scrapper. The crit ATO goes reeeeally well with TW.  

Let me know if you want to see a scrapper build to compare to. 

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