Here is my Mids build:
Villain Plan by Mids' Reborn : Hero Designer 2.7.2.10 https://github.com/Crytilis/mids-reborn-hero-designer
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Level 50 Magic Brute Primary Power Set: Radiation Melee Secondary Power Set: Bio Armor Power Pool: Fighting Power Pool: Leadership Power Pool: Speed Power Pool: Leaping
Villain Profile: Level 1: Radioactive Smash -- SprBrtFur-Acc/Dmg(A), SprBrtFur-Dmg/Rchg(3), SprBrtFur-Dmg/EndRdx/Rchg(5), SprBrtFur-Acc/Dmg/EndRdx/Rchg(5), SprBrtFur-Rech/Fury(7) Level 1: Hardened Carapace -- Ags-ResDam/EndRdx(A), GldArm-3defTpProc(3), Ags-ResDam(7), Ags-ResDam/EndRdx/Rchg(9) Level 2: Proton Sweep -- SprUnrFur-Acc/Dmg(A), SprUnrFur-Dmg/Rchg(11), SprUnrFur-Acc/Dmg/Rchg(11), SprUnrFur-Dmg/EndRdx/Rchg(13), SprUnrFur-Acc/Dmg/EndRdx/Rchg(13), SprUnrFur-Rchg/+Regen/+End(40) Level 4: Environmental Modification -- LucoftheG-Def/Rchg+(A), GifoftheA-Def(37), GifoftheA-Def/EndRdx(46), GifoftheA-Def/EndRdx/Rchg(48), LucoftheG-Def/EndRdx(48) Level 6: Fusion -- RechRdx-I(A) Level 8: Inexhaustible -- Prv-Heal(A), PwrTrns-+Heal(9), PwrTrns-EndMod(17), Prv-Absorb%(31), PrfShf-End%(34) Level 10: Adaptation Level 12: Boxing -- Acc-I(A) Level 14: Tough -- Ags-ResDam/EndRdx(A), Ags-ResDam(15), Ags-ResDam/EndRdx/Rchg(15), StdPrt-ResDam/Def+(17) Level 16: Ablative Carapace -- DctWnd-Heal/EndRdx(A), DctWnd-Rchg(23), DctWnd-Heal/Rchg(23), DctWnd-Heal/EndRdx/Rchg(25), DctWnd-Heal(45) Level 18: Irradiated Ground -- FuroftheG-Acc/Dmg(A), Erd-%Dam(19), ScrDrv-Dmg/EndRdx(19), FuroftheG-ResDeb%(21), ScrDrv-Dam%(21), TchofLadG-%Dam(27) Level 20: Evolving Armor -- UnbGrd-ResDam/EndRdx/Rchg(A), UnbGrd-ResDam/EndRdx(25), UnbGrd-ResDam(31), UnbGrd-Max HP%(31), UnbGrd-EndRdx/Rchg(40), UnbGrd-Rchg/ResDam(45) Level 22: Assault -- EndRdx-I(A) Level 24: Weave -- LucoftheG-Def/Rchg+(A), GifoftheA-Def/EndRdx(46), GifoftheA-Def(46), GifoftheA-Def/EndRdx/Rchg(48) Level 26: Devastating Blow -- SprBlsCol-Acc/Dmg(A), SprBlsCol-Acc/Dmg/EndRdx(27), SprBlsCol-Acc/Dmg/Rchg(29), SprBlsCol-Dmg/EndRdx/Acc/Rchg(29), SprBlsCol-Rchg/HoldProc(42) Level 28: DNA Siphon -- Prv-Heal/Rchg(A), Prv-Heal(37), FuroftheG-Acc/Dmg/End/Rech(39), FuroftheG-Acc/End/Rech(39), ScrDrv-Dam%(45) Level 30: Hasten -- RechRdx-I(A) Level 32: Atom Smasher -- SprAvl-Acc/Dmg(A), SprAvl-Dmg/EndRdx(33), SprAvl-Acc/Dmg/EndRdx(33), SprAvl-Acc/Dmg/Rchg(33), SprAvl-Acc/Dmg/EndRdx/Rchg(34), SprAvl-Rchg/KDProc(34) Level 35: Genetic Contamination -- Arm-Dmg(A), Arm-Acc/Dmg/Rchg(36), Arm-Dmg/EndRdx(36), Arm-Acc/Rchg(36), Arm-Dam%(37), ScrDrv-Dam%(50) Level 38: Parasitic Aura -- NmnCnv-Heal/EndRdx(A), NmnCnv-EndRdx/Rchg(39), NmnCnv-Heal/Rchg(40), NmnCnv-Heal/EndRdx/Rchg(43), NmnCnv-Heal(50), NmnCnv-Regen/Rcvry+(50) Level 41: Maneuvers -- LucoftheG-Def/Rchg+(A), ShlWal-ResDam/Re TP(42), Rct-ResDam%(42) Level 44: Tactics -- EndRdx-I(A) Level 47: Combat Jumping -- LucoftheG-Def/Rchg+(A) Level 49: Vengeance -- LucoftheG-Def/Rchg+(A) Level 1: Brawl -- Empty(A) Level 1: Prestige Power Dash -- Empty(A) Level 1: Prestige Power Slide -- Empty(A) Level 1: Prestige Power Quick -- Empty(A) Level 1: Prestige Power Rush -- Empty(A) Level 1: Prestige Power Surge -- Empty(A) Level 1: Fury Level 1: Sprint -- EndRdx-I(A) Level 2: Rest -- RechRdx-I(A) Level 4: Ninja Run Level 2: Swift -- Run-I(A) Level 2: Health -- Pnc-Heal/+End(A), Mrc-Rcvry+(43) Level 2: Hurdle -- Jump-I(A) Level 2: Stamina -- PrfShf-End%(A), PwrTrns-+Heal(43) Level 10: Defensive Adaptation Level 10: Efficient Adaptation Level 10: Offensive Adaptation Level 50: Agility Core Paragon Level 50: Assault Radial Embodiment Level 50: Mighty Core Final Judgement Level 50: Reactive Core Flawless Interface Level 50: Ageless Core Epiphany ------------
I focused on fire farming, but it can do pretty much anything. The +regen powers shore up the missing resistance pretty well. I usually can use Parasitic Aura for 1 mob and Ablative Carapace on the next and do fine. If you wanted to make it more well-rounded on the resistance, you can probably move some slots around.