I also had this occur to me.
It happened with the second mission Redside from Slot Machine in St. Martial.
The mission was a timed mission and it autocompleted as a failure when i clicked on the door to enter.
Machines 2-4 shold run COH fine.
#4 would be the cheapest option, but personally i would go with #2.
The Ryzen processor should have no issues, but its a newer chip, and Ive never run COH on it, so Im not certain about COHs' performance with it.