Hello, glad you're liking the Regen revamp!
Yes, nuRegen is a bit more streamlined and user friendly, but a lot of its identity still remains intact. It's still going to fold easily to debuffs, so you'll have to choose your targets carefully before you crumple!
As always, having crowd control options are a huge boon when running Regen. If mobs are unable to attack you, then that's less attention you have to spend on healing!
I'd also recommend looking into pool powers and picking your favorite defensive clickies. Having an extra panic button online along with your other incredible options will keep you standing if things start getting rough. Might I suggest Rune of Protection?
Of course, I'm always open to any questions you might have, and there's numerous threads floating around the various Archetypes sections where I've offered advice as well!