Poison/Dual Pistols help

[Sechill71511]

just trying to get some help with a Poison/Dual Pistols build, i never played poison def before not sre what powers to pick i liked having DP for the acid ammo for extra debuff, not sure how to build this, if i can get some help and maybe a mids build i would appreciate it

[Knottewe]

I use Dark instead of pistols for the immobilize, heal and snipe (Moonbeam's quick snipe can hit for 600-700 damage against debuffed targets) but Im sure you can pull some useful info from the build.

 

 

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Level 50 Science Defender
Primary Power Set: Poison
Secondary Power Set: Dark Blast
Power Pool: Speed
Power Pool: Leadership
Power Pool: Fighting
Power Pool: Concealment
Ancillary Pool: Psychic Mastery

Hero Profile:
Level 1: Alkaloid

• (A) Preventive Medicine - Heal
• (3) Preventive Medicine - Heal/Endurance
• (3) Preventive Medicine - Endurance/RechargeTime
• (5) Preventive Medicine - Heal/RechargeTime
• (5) Preventive Medicine - Heal/RechargeTime/Endurance
• (7) Preventive Medicine - Chance for +Absorb
  

Level 1: Dark Blast

• (A) Superior Defender's Bastion - Accuracy/Damage
• (7) Superior Defender's Bastion - Damage/Recharge
• (9) Superior Defender's Bastion - Damage/Endurance/Recharge
• (9) Superior Defender's Bastion - Accuracy/Damage/Endurance
• (11) Superior Defender's Bastion - Accuracy/Damage/Endurance/Recharge
• (11) Superior Defender's Bastion - Recharge/Chance for Minor PBAoE Heal
  

Level 2: Envenom

• (A) Shield Breaker - Chance for Lethal Damage
• (15) Shield Breaker - Accuracy/Defense Debuff
• (17) Shield Breaker - Defense Debuff
• (17) Touch of Lady Grey - Chance for Negative Damage
• (19) Achilles' Heel - Chance for Res Debuff
  

Level 4: Weaken

• (A) Cloud Senses - ToHit Debuff
• (19) Cloud Senses - Accuracy/ToHitDebuff
• (21) Cloud Senses - Accuracy/Recharge
• (21) Cloud Senses - ToHit Debuff/Endurance/Recharge
• (23) Cloud Senses - Accuracy/Endurance/Recharge
• (23) Cloud Senses - Chance for Negative Energy Damage
  

Level 6: Moonbeam

• (A) Apocalypse - Damage
• (25) Apocalypse - Chance of Damage(Negative)
• (25) Apocalypse - Damage/Endurance
• (27) Sting of the Manticore - Accuracy/Damage
• (27) Sting of the Manticore - Chance of Damage(Toxic)
• (29) Sting of the Manticore - Damage/Endurance
  

Level 8: Elixir of Life

• (A) Steadfast Protection - Resistance/+Def 3%
• (29) Steadfast Protection - Knockback Protection
  

Level 10: Hasten

• (A) Recharge Reduction IO
• (31) Recharge Reduction IO
  

Level 12: Maneuvers

• (A) Luck of the Gambler - Recharge Speed
• (31) Luck of the Gambler - Defense/Endurance
• (31) Kismet - Accuracy +6%
  

Level 14: Tactics

• (A) Adjusted Targeting - To Hit Buff
• (33) Adjusted Targeting - To Hit Buff/Endurance
  

Level 16: Boxing

• (A) Accuracy IO
  

Level 18: Paralytic Poison

• (A) Basilisk's Gaze - Accuracy/Hold
• (33) Basilisk's Gaze - Accuracy/Endurance/Recharge/Hold
• (33) Basilisk's Gaze - Chance for Recharge Slow
• (34) Basilisk's Gaze - Endurance/Recharge/Hold
• (34) Neuronic Shutdown - Chance of Damage(Psionic)
• (34) Ghost Widow's Embrace - Chance of Damage(Psionic)
  

Level 20: Tough

• (A) Gladiator's Armor - TP Protection +3% Def (All)
  

Level 22: Weave

• (A) Luck of the Gambler - Defense/Endurance
• (36) Luck of the Gambler - Recharge Speed
  

Level 24: Stealth

• (A) Luck of the Gambler - Recharge Speed
• (36) Luck of the Gambler - Defense/Endurance
  

Level 26: Poison Trap

• (A) Basilisk's Gaze - Accuracy/Endurance/Recharge/Hold
• (37) Basilisk's Gaze - Endurance/Recharge/Hold
• (37) Fury of the Gladiator - Chance for Res Debuff
• (37) Armageddon - Chance for Fire Damage
• (39) Ghost Widow's Embrace - Chance of Damage(Psionic)
• (39) Unbreakable Constraint - Chance for Smashing Damage
  

Level 28: Torrent

• (A) Superior Vigilant Assault - Accuracy/Damage/Endurance
• (36) Superior Vigilant Assault - Damage/Endurance/RechargeTime
• (39) Superior Vigilant Assault - Accuracy/Damage/Endurance/RechargeTime
• (40) Annihilation - Chance for Res Debuff
• (40) Overwhelming Force - Damage/Chance for Knockdown/Knockback to Knockdown
• (40) Force Feedback - Chance for +Recharge
  

Level 30: Tenebrous Tentacles

• (A) Cloud Senses - ToHit Debuff
• (42) Cloud Senses - Accuracy/ToHitDebuff
• (42) Cloud Senses - Accuracy/Recharge
• (42) Cloud Senses - ToHit Debuff/Endurance/Recharge
• (43) Cloud Senses - Accuracy/Endurance/Recharge
• (43) Cloud Senses - Chance for Negative Energy Damage
  

Level 32: Venomous Gas

• (A) Dark Watcher's Despair - To Hit Debuff
• (43) Dark Watcher's Despair - To Hit Debuff/Recharge/Endurance
• (45) Dark Watcher's Despair - To Hit Debuff/Endurance
• (45) Dark Watcher's Despair - Recharge/Endurance
  

Level 35: Life Drain

• (A) Superior Vigilant Assault - RechargeTime/PBAoE +Absorb
• (45) Superior Vigilant Assault - Damage/RechargeTime
• (46) Superior Vigilant Assault - Accuracy/Damage
• (46) Theft of Essence - Healing
• (46) Theft of Essence - Chance for +Endurance
  

Level 38: Dominate

• (A) Lockdown - Chance for +2 Mag Hold
  

Level 41: Mind Over Body

• (A) Unbreakable Guard - Resistance/Endurance
• (48) Unbreakable Guard - Resistance
  

Level 44: World of Confusion

• (A) Coercive Persuasion  - Confused
• (48) Coercive Persuasion  - Confused/Recharge
• (48) Coercive Persuasion  - Accuracy/Confused/Recharge
• (50) Coercive Persuasion  - Accuracy/Recharge
• (50) Coercive Persuasion  - Confused/Endurance
• (50) Coercive Persuasion  - Contagious Confusion
  

Level 47: Grant Invisibility

• (A) Luck of the Gambler - Recharge Speed
  

Level 49: Vengeance

• (A) Luck of the Gambler - Recharge Speed
  

Level 1: Brawl

• (A) Empty
  

Level 1: Prestige Power Dash

• (A) Empty
  

Level 1: Prestige Power Slide

• (A) Empty
  

Level 1: Prestige Power Quick

• (A) Empty
  

Level 1: Prestige Power Rush

• (A) Empty
  

Level 1: Prestige Power Surge

• (A) Empty
  

Level 1: Sprint

• (A) Celerity - +Stealth
  

Level 1: Vigilance 

Level 2: Rest

• (A) Empty
  

Level 1: Health

• (A) Panacea - +Hit Points/Endurance
• (13) Miracle - +Recovery
  

Level 1: Hurdle

• (A) Jumping IO
  

Level 1: Stamina

• (A) Performance Shifter - Chance for +End
• (13) Performance Shifter - EndMod
• (15) Efficacy Adaptor - EndMod
  

Level 1: Swift

• (A) Run Speed IO
  

Level 50: Ageless Core Epiphany 

Level 50: Degenerative Core Flawless Interface 
Level 50: Nerve Core Paragon 
Level 0: The Atlas Medallion 
Level 0: Portal Jockey 
Level 50: Melee Core Embodiment 
Level 50: Ion Radial Final Judgement 
------------

 

[Ankhammon]

It depends a little on how you want to play. Do you want to have the heal, mez prot and rez?

 

On my Poison char I, selfishly, did not and subbed in tough line instead. 🙂

 

So I ended up with all the rest in the set and each is good or very good in what it does. The Key powers are Envenom, Weaken, Poison Trap and Venomous Gas. 

Many will tell you that Paralytic Poison is good because it's very proctastic. They are right, but you will have the redraw to deal with. 

I do like Neurotoxic Breath because of the -81.25% Rech on it that lasts 20 seconds, but it's up to you if you like those kinds of powers. I'd use it in that combo till Poison Trap gets loaded or you pistols get filled out completely. Then I might respec out of it depending. 

 

 

[ChetManly]

I just got mine to 32, and I've taken every power in the set. I feel like i've read a bunch of posts of people not being stoked about Poison or this combo, but I love it. I slotted all my primaries up pretty heavy so far and basically just ACC in the guns, utilizing the secondary effects for debuffing ATM.

Ank pretty much said it but ill add...

...that I have the heal and it's come in handy about a jillion times already. I have 1 Rech and 2 Heals in it currently.

...Antidote is great Mez Protec with the added bonus of Resist to some tougher Dam types, Toxic and Cold I think. I Rech and 1 DamRes ATM although that is a bit overkill with Hasten and i'll prolly spec out.

...The Rez. It's a rez. I regretted taking it at first and then needed it literally 5 times on the next mish. 1 Recharge

...I like trying to work the hold in with the Poison Trap Hold component and use it all the time. I currently have this 5 slotted, 2 ACC, 1 Rech, 1 Hold, 1 End Mod. I wanna see how and what that does but will likely change it. I'm not seeing any big -END -Rec so far.

 

I'ts not much, but maybe it'll be helpful. If I think of more, i'll post it up.

 

-Chet

[Frosticus]

You def want:

envenom, weaken, poison trap and venomous gas

 

I strongly recommend putting the available damage procs and -res procs into envenom, weaken and PT

 

They proc pretty reliably in weaken and envenom, but also help to show you how big (small) the aoe is against the group as the power effects are otherwise quite minimal.

PT is of course a proc bomb. Love it.

 

Neuro breath is a pretty good power. I definitely use it up until I have venomous gas. Once I have VG I want to be up close right away.

I put the smashing damage proc in neuro. Again it helps show just how big the area of effect is as it procs well. Plus you may well do some damage if you are taking the time to cast it.

 

The heal, ally mez protection and rez are all good enough powers. You aren't a healor so don't try to be but helping patch someone up between spawns can be valuable. Mez protection really helps most squishies play more confidently, but it can get time consuming.  The rez is a rez. Poison is about facilitating quick clear speeds. A downed teammate impedes that. 

Of those three powers I would take the rez. But only if I have vengence (which I do). Veng then rez = faster clear times for the team. 

Having the heal in that situation can trap you into trying to keep them alive, but it is faster for the team to just let them die then veng+rez

 

chem rounds stack nicely with strong -dam of weaken and venomous gas and get boosted nicely by all the -res you toss out (also a reason for the -res procs). It should really start to click once venomous gas is in place.