Is it the most fun of the game to look into how to reduce endurance issues? Not really, but there are a lot of ways to compensate. Mine usually wind up with end reduction SO or IO (at 32+), but if I'm running something with a resistance power, I will two slot Unbreakable Guard for the end reduction. (several other sets do it as well, but that's my goto at level 17+)
There are some powers out there that seem end heavy, but it's never been the end of the world. If they reduced all end cost, I would probably not even notice it at this point.