With Soothing Aura slotted like how I have it in the build I posted, it heals for approx 196 HP every couple of seconds...not counting the chances to proc. Nullify Pain, the PBAoE Heal, with my slotting, heals for 281 HP every (roughly) 3 seconds. Combined, that's a decent amount of healing.
Also, your DP attacks, if you put,say, the Ice Mistral Chance For Cold Damage in your attack, it will have a chance to fire regardless if you have Cryo Ammo selected or not. Meaning, any proc, even if it *should* only have a chance to proc based on the certain ammo type, will have that chance to proc NO MATTER the ammo type selected. Might be a bit of info you didn't know, didn't wanna know, or might actually give you a couple of ideas if you want to proc out your attacks.
Oh, crap. Just realized I only slotted one set of the Defender IO...I forgot to slot Superior Vigilant Assault (has some nice set bonuses).
Either way, I have several DP toons, and it's a fun set. The only Pain Domination toon I have is my Mercs/Pain MM, and I like it. I wish that Suppress Pain (the same as a Defender's Soothing Aura) worked like Soothing Aura. On MMs/Corrs it gives a Regen bonus,NOT a flat out heal every couple of seconds. BUT, the procs still fire off on everyone 😃