Thank you, but let us not oversell the Snarky. (especially to someone who already scratched the gold electroplate off the steel!) I, once or twice a year, do completionist attempts. Which go well if I do Red, and have had decidedly mixed results on Blue and Red/Blue/Gold. These are set at +0/x1 and are not near the stress and difficulty of each mission being a possible end of the run.
I have seen some SG mates take on a similar challenge, allowed to team together, one death and out. It was a meat grinder they ran for two? months. Everytime someone died they rerolled and joined back in. At it every night. No idea how far the most successful got.
Finally, I am sorry that you were offended. Careful reading will reveal I am not apologizing for what I said. I am who I am. In my view I pointed out basic facts, in a Snarky way. I may be wrong. You may take the first toon and frog march to 50. A 50 of almost any AT/Powerset can handle +4. My old Brutes could handle +4 (on a team) by about late 20s early 30s. I see the issue as low level. Although any fight at high level could end the run, I see huge roadblocks at 1-30 running at +4. If my saying something about it offends you.
Finally, I would like you to meet my heroes....