I've been testing a variety of options lately while waiting for Tankers to officially replace Brutes, and I've noticed we have a fundamentally flawed assumption.
Capped defense and resistance is not, and should not, be the goal.
I came to this realization while running a blaster with 40%/60% defense/resist and my health never moved.
Now, what to do with this information. Obviously we'd want to direct those resources away from durability into offense. However, extra offense is sort of hard to come by. While farming, you're at the damage cap nearly 100% of the time through normal slotting power use and the deluge of inspirations. Additionally, Firey Aura just gets capped fire resistance basically for free, so there's not even a resource to move around there. We can't just get rid of Fiery Aura, since it contains Burn and Fiery Embrace; none of the other sets come close to that amount of offense.
Where's that leave us? I guess it means more recharge. Although that's sort of a limp noodle. If you're doing a lazy rotation, everything is as slow as Ball Lightning, and even a capped recharge Ball Lightning (which is unfeasible for Brute farming) still takes longer than the animation times of whatever other powers you're using. I guess that's when you sneak in the Embrace/Build Ups/whatevers?
I'm not sure what to do with unlimited budget builds now. The good news is that it's cheaper to get into farming on the ground floor since all those Lord of Winter sets aren't really necessary.
PS. Blaster farming sucks. Half the mobs run when you hit them with your first power.
PPS. I hope everyone has your Tank farmer ready to go because Brutes are on death's door.