Actually, Savage and Regen has a bit of synergy. Since Savage has an innate +recharge component, and regen is clicky heavy.
Savage/regen brute. Actually in the game. Already a thread in the brute forums about how Savage is under performing.
Synergy or not, Savage's damage is lacking. /regen for a brute only really comes into its own with IOs factored in and is going to have issues in various situations before that. /wp is a far better set on a brute.