Bear with me everyone, slight digression for @Doomguide2005. My main, Kameron Daniels, (pictured in avatar) is a level 50 Goldsider, got the incarnates. So, no, you cannot get to Ouroborous as a Goldsider, so you can't do the Mender Ramiel missions, or talk to Prometheus or any of that. You level up and you earn everything through threads and shards, and it's totally doable, you just haven't anything to, not shortcut things for you but to point the way. You can however access Ouro missions, but only Praetorian ones, via a crystal in an SG base, so that really helps. Plus you can do Cathedral of Pain, the Summer Block Buster, and all of the iTrials.
Last Bastion is a bugbear for me as a goldsider, in that it is an area of Praetoria that no non crossing Praetorian can go! You need to work with Number Six to access it and other Praetorian instances that are closed to actual Goldsiders (as opposed to Goldsider originated toons).
Lore-wise? You don't learn anything about the Well if I'm staying in character now, you just find yourself getting stronger and more powerful. Hmm, that at least might need to be addressed!
Ok, happy to answer more questions on incarnate Goldsiders as I have spent the last six months pushing against as many limits as I can.
Back to the topic at hand, thanks for everyone's forbearance.