The Mistborn trilogy has massive world building along with the story. And in the end you find out that almost every detail that has come up as the story went along matters. It all ties into a massive plot that explains everything and depends on everything. Very satisfying in its way.
In Marvel comics, things are messy. 60 years of history with lots of different comics, storylines, etc. Things exist that are unrelated to one another - and then they bump into each other.
But the MCU rewrites Marvel to fit the Mistborn model. A Stark or alien technology explains almost all advanced technology. Tony built Ultron instead of Henry Pym. Vulture gets his wings from alien technology.
While I love Mistborn, I reject the same everything ties together in the MCU. I don't want the entire world of superheroes to have just a few things that drive the whole world.
CoH has lots of different villain groups, organizations, etc. It also has Nemesis. And when you play arcs you discover connections between different groups. So how do you want the CoH lore to go?
Do you want it all to ultimately make sense? These are the sources of power, the things that changed our world into the CoH world. This is the grand plot behind everything?
Or do you want it just chaotic and random. Hellions worship demons and the Banished Pantheon worships evil gods and someone else worships demons and there are no connections between them - there are plenty of demons to go around? There are endless mad scientists creating freakshow, sky raider technology, etc. It is not all a Nemesis plot.