Temporary Invulnerability, Unyielding, and Invincibility are your toggles. Temporary Invuln adds smashing/lethal resistance. Unyielding is your mez protection. Invincibility is your taunt aura, and it also gives you scaling defense depending on how many mobs are in range of it. These toggles and Dull Pain, your trouble button, are the heart of the set. Before level 22 or so endurance reduction is your only priority in the toggles.
Dull Pain gets six slots seeking to maximize heal and recharge. These four are your core powers.
The rest should be taken eventually, except for Unstoppable, which is a free pick of something else at 32 or 38. Tough Hide gets two or three slots of defense. The other passives are fine with their default slot. This is a great blessing for your attacks. They should be taken eventually but they aren't priorities.
Get endurance under control. Give slots to Health and frankenslot the recovery uniques.
Once endurance is a solved problem, you will eventually want Tough and Weave. This means wasting a selection on Boxing or Kick first. At least you don't have to do the Stamina grind any more.