Good question. When you’re on a Tanker in solo play, the increased number of targets for Power Crash doesn’t matter unless your above 10 mobs saturation. You’re best bet is to find the strongest target in the spawn and burn them down with Total Focus/Energy Transfer while using Whirling Hands/Power Crash in-between to take out the garbage.
As a Tanker in teams, your focus switches to maintaining aggro, you can switch your focus. The additional number of targets for Power Crash will come in handy even if you’re past target saturation, because Gauntlet will Proc and help to keep the aggro centered as your teams AoEs annihilate the mob cluster. Through this, maintain your focus on hard targets and you’ll be fine.