So, I took my remade (from Live) tank and all his Frankenslotted glory and rebuilt him, very closely to your posted build above. Got almost the identical stats in Mids:
He was 50 +0, at the time, so farmed some Council to get his Alpha slot unlocked. Took Resilient Alpha (T3), 'cause I like S/L capped and the snips are with it on.
I haven't really delved into the 801 AEs, so I use "Just Teh Council" and "Big Mobs Tunnel Fire Farm" for informal benchmarking. My dude hangs as well as NUTCRKR in both, at +4/8. Like NUT, the bosses took some time, but I was never in any true peril (council was a joke, obviously, and the fire was manageable), with only munching the skittles that dropped, during the run.
Let's go run a solo ITF, I said to the voice in my head (I know I'm OK, because the voice tells me so...), but I dropped the diff to +3/8. Same as AE, mobs disappear quickly, except for the bosses, so I just drag them along until the AOE eventually drops them, as well. Saved the scantily clad ladies and headed to the platform. I avoided the stairs and was almost done clearing the platform, with a single boss and the EB Minotaur left. Must have gotten too close to the stairs because the dark ambush began. Not sure how many times I was hit, but the defense degradation was immediate, sudden and overwhelming. I face planted in about 5 seconds. Any idea why?