You likely have combat mode flagged in Mids. Infiltration loses 100% of its benefits while in combat.
Additionally, I believe that Athletic Run and Infiltration don't stack, in game will only take Infiltration into consideration as it has higher stats than Athletic Run.
For "maxing out" stuff when using Infiltration, I usually 3 slot it with either Blessing of the Zephyr (if I need KB protection) or Winter's Gift (if I don't).
It doesn't ED max anything, but both sets improve both the run and jump aspects of Infiltration, so you get more bang for your buck.
If you happen to have enough slots lying around, 3 slot one of the above sets, 1 slot the movement speed IO from the other set (50+5 if you really want to max stuff) then use the +jump unique and the +run unique as those are separate from ED.
I don't think its worth 6 slotting infiltration though.