Honestly, most "tweaked" builds tend to fall apart at some point during the leveling process.
I wouldn't recommend doing more than adding the "gotta haves"
(The Endurance boosters in Health.
Performance Shifter.
The (+3% Defense) Resist IOs
The (+Resist) Defense IOs.
Stick to SOs until your 30's.
Once you can drop a full 6 slots on Granite, look at an IO rebuild.