I hope that you wouldn't have these homeless as the enemies you fight. As @Thrones intimated, it's unfortunate that you basically strip The Lost of their power in the name of "saving" them. It would be cool if you wrote an arc centered around a group that was trying to rehabilitate some member of The Lost, and finding a way to reverse the physical changes while retaining the power-granting ones, perhaps with an eye toward community outreach and possible hero work. It'd also be interesting if the usual actors, (Crey, perhaps Arachnos, and maybe even some corrupt PPD or Freedom Corps members), were trying to weasel their way into this program and hog the results to themselves...