From a quick glance at your generic IO build. You need to move some slots around, slotting 6 IO of the same type in any power is a waste due to Enhancement Diminishing Returns. Any more than 3 of same enhancement is just a waste. I would stop at 2.
You have Fast Healing 6 slotted with Heal enhancements but only 3 will count,due to ED. So you are better off either putting other enhancements in those slots,or moving the slots to another power. Same for the Stamina and Quick Recovery powers.
You could move some of those slots to Tough,Weave and Maneuvers. You may as well maximize those powers as well as try and minimize the end drain.
Also I would move the defense IOs from Invisibility to Stealth.