In D&D 4e there's a concept of minions.
Minions do the same damage as a normal NPC. The players still have to waste actions attacking them, because they can be dangerous... but they have 1hp.
You know when you see those ARPGs where hoards of enemies get easily one-shotted? Could the City of Heroes engine handle this kind of thing? I mean there's already Gang War ...
I played the Praetoria arc and it feels like SO MANY times there are occurrences when there could have been ghoul hoards, instead it's just a few and they aren't quite one-shottable.
It feels like a missed opportunity to make the players feel like EPIC superheroes!
So my suggestion is another class of super-weak enemy in the style of D&D 4e Minions, which should be deployed in great numbers. Not in every mission, ofc, but in some (especially timed ones, perhaps, for drama).